Martin L. Pall, PhD, professor of Biochemistry and Basic medical Science at Washington State University stated: "Peroxynitrite reacts with and inactivates several of the enzymes in mitochondria so that mitochondrial and energy metabolism dysfunction is one of the most important consequences of elevated peroxynitrite."
Translation: When the mitochondria have suffered enough free radical damage as to become dysfunctional, energy production is impaired. Your cells do not get the amount of energy they need to function properly. Your cells may function at a level below the optimum although you probably won't feel it.
There is yet one more free-radical mitochondrial consequence as a result of low glutathione levels that you "will" be aware of. Richard Van Konynenburg, PhD, wrote: The resulting partial blockades in the Krebs cycles and the respiratory chains in the red, slow-twitch skeletal muscle cells decease their rate of production of ATP. Since ATP is what powers muscle contractions, the lack of it produces physical fatigue. It becomes chronic because GSH[glutathione] remains depleted."
You might think of free radicals as a hand of marauders circling an oil tanker, preparing to hijack the precious commodity that fuels cars and trains and pretty much the entire Western World. Glutathione molecules could be considered a group of highly efficient bodyguards - handling out electrons and turning vicious marauders into mild-mannered bystanders.
Keith Carey with MaxGXL and MaxWLX
Keith Carey and His Business, Max International Products: MaxGXL and MaxWLX
Friday, September 12, 2008
Peroxynitrite is Truly Pernicous!...
Tuesday, September 9, 2008
Glutathione Praise from Dr. Keller...
As you understand this intricate energy creation process, perhaps you will appreciate more a statement by the creator of MaxGXL, Dr. Robert H. Keller. Dr. Keller said that glutathione is "critical to cell functions such as the TCA(Kreb) cycle and then the respiratory chain that uses 4 molecules of ATP to generate 32 molecules of ATP."
Is it vital for you to have those glutathione bodyguards on energy duty? Van Konynenburg certainly thinks so as he wrote, "GSH [glutathione] plays very important roles in maintaining mitochondrial function and integriry."
Perhaps it's enough to remember that glutathione is there to assure that the creation of cellular energy is not hampered by free radical damage. While this is not by any means the only role glutathione plays in keeping your body running smoothly, it is a vitally important role. Now you have one more reason to appreciate Dr. Keller's marvelous, patented product!
Tuesday, August 26, 2008
The Role of Glutathione in Energy Production...
These are questions we would all like answers to, but not if they make us feel like we're back in Chemistry 101!
Hopefully, what you read below will provide a non-technical explanation for these questions.
Oxidation is like a flame, wonderful when harnessed, dangerous when out of control. When we are young, the oxidation necessary for energy production is highly efficient with only a small amount of oxygen not utilized. Even this minor oxygen loss (1-3%) unfortunately results in the production of free radicals. And this is where glutathione comes in to neutralize those free radicals.
A one-to-three percent oxygen loss causing free-radicals production doesn't sound too bad, does it? But say you are no longer 20 years of age and correspondingly, your cellular mitochondria are not as efficient as they once were. More and more free radicals are generated in the oxidative energy process and they are, in turn, damaging the
mitochondria themselves.
The powerful antioxidant, glutathione, quenches a number of free radicals, including the highly dangerous hydroxyl radical by donating an electron. Glutathioneitself does not become a free radical even though it has given up an electron.
No wonder it is called the Master Antioxidant!
Now that it is quenched, the extremely harmful hydroxyl radical is halted from its real dirty work: generating other free radicals like peroxynitrite and the radicals of oxidized fats (lipids).
Glutathione has just halted a literal cascade of free radicals by quenching the hydroxyl free radical. But you need to know just what a favor glutathione has done for you in preventing peroxynitrite production.
If you want More Information...Feel Free to call the person Above or visit his MaxGXL Site...
Tuesday, August 19, 2008
Is MaxGXL Glutathione A Scam?...
Simply put, glutathione (GSH) is the body's master antioxidant. It is a small protein produced naturally in our cells when certain required elements are present. It functions both as an antioxidant and an antitoxin and is a major defense system against illness and aging. Our glutathione level actually indicates our state of health and can predict longevity. Although there are more than 60,000 published papers on the beneficial effects of glutathione replacement, it is still largely ignored by mainstream medicine. In the near future the importance of glutathione will be widely recognized because it has the ability to boost the immune system and fight off the damage of free radicals on the cells.For More Information,
Please Contact:
Keith Carey - 818-510-4456
or
Take A Tour and Get Acquianted!!!
http://www.LivinToTheMAX.com
Introducing Dr. Keller and MaxGXL with Steve Scott...
Glutathione has been shown to slow down the aging process, detoxify and improve liver function, strengthen the immune system, and reduce the chances of developing cancer. glutathione also works to help improve mental functions, increase energy, improve concentration, permit increased exercise, and improve heart and lung function - just to name a few.
MaxGXL - The Story...
The Breakthrough...
After reviewing subject lab results for years, Dr. Keller noticed a trend. He kept seeing significantly low levels of uric acid in subjects with immune disorders. He decided to explore this finding, and his initial research concluded that uric acid is the last antioxidant at the body's disposal when all the normal antioxidants have been exhausted.
As Dr. Keller has always been a strong advocate of nutrition, he went back in the literature, seeking the answer to one question: If uric acid is the body's last defense, then what is the first? His investigation led him to a substance called glutathione.
Glutathione (GSH): The Master Antioxidant...
Glutathione (GSH) is a small protein produced naturally in our cells if the requisite precursors are present. It functions both as an antioxidant and an antitoxin and is a major defense system against illness and aging. Our glutathione level actually indicates our state of health and can predict longevity. It has been suggested that in the future, GSH levels will be closely monitored. There are over 60,000 medical articles currently published on GSH, yet most health professionals have only a vague idea of its significance. In the near future, the importance of glutathione will be widely recognized.
After learning of the importance of GSH, Dr. Keller needed to test the hypothesis that the levels of GSH in subjects with immune disorders were, in fact, severely diminished. To get a current and accurate gauge of a subject's GSH level, Dr. Keller knew the test must measure GSH inside of lymphocytes (activated cells); however, no such lab test existed.
Using a state-of-the-art medical laboratory, Dr. Keller and his team of scientists developed a proprietary lab test to measure levels of GSH inside the lymphocytes.
The tests confirmed the hypothesis. People who are stressed, aging, lacking sleep, or with any prolonged illness utilize glutathione at an accelerated rate resulting in decreased bodily stores, weakened defenses, and increased risk of illnesses including accelerated aging.
The Challenge...
It was clear that the GSH levels needed to be replenished in these subjects. But how? glutathione is produced naturally from three amino acids: glycine, glutamine, and cysteine. These essential precursors of GSH must be able to make it from the mouth to the gut, then through the cells walls and subsequently the mitochondrial membrane. There lies the challenge.
Unfortunately, we can't raise our body's GSH level with ordinary foods or pure L-glutathione is present in many fruits, vegetables and meats, this protein is instantly broken down during digestion into its three amino acids. Cysteine, or N-acetylcysteine (NAC), is the most important of these precursors and is the main limiting factor necessary for the body to manufacture GSH. Alone in the gut after digestion, cysteine is treated as a free radical and rapidly oxidized. Consequently, only a very small percentage reaches our bloodstream and cells.
Furthermore, GSH is always in great demand and is rapidly consumed, so any GSH that is made will be used up quickly making it even more difficult to increase this level.
The Solution: MaxGXL...
Feel Free to visit
